The Arkansas Department of Health, Section of Emergency Medical Services, has issued new information about the use of xylazine in illicitly manufactured opioids.

In addition to high-potency opioids, xylazine is now being used as an adulterant compound in illegally produced opioids.Xylazine, a non-opioid alpha-adrenergic agonist, is legally administered to animals by veterinarians as a sedative, anesthetic, muscle relaxant and analgesic. In humans, xylazine can cause respiratory depression, bradycardia, various forms of heart block, and death. A Drug Enforcement Administration (DEA) license is not required to obtain xylazine, and this factor makes the drug more readily accessible.

Read the full memorandum here